What is Radiesse?
Radiesse is a dermal filler used to smooth out mild to severe wrinkles and folds. Radiesse provides immediate volume replacement plus long-term improvement by stimulation of collagen and elastin production.
Radiesse is used to reduce the signs of aging. It is most commonly used to add lost volume due to aging to areas of the face and the back of the hands. It is FDA approved to improve the appearance of facial wrinkles and nasolabial folds.
Radiesse is a biocompatible, biodegradable, and resorbable bio-stimulatory filler. It is the first and only FDA-approved calcium hydroxyapatite (CaHA) microsphere that can stimulate the endogenous production of collagen.
What Makes Radiesse Good at Fighting Signs of Aging?
Radiesse is a unique product because it provides both volume replacement and collagen biostimulation as a primary mechanism of action.

What Causes Skin To Change As We Age?
As we age, along with environmental factors such as sun damage, our body reduces the capacity of making the two important components – collagen and elastin fibers, which are the building blocks for skin strength and elasticity to keep skin tone and good facial contour. Reduced amounts of collagen and elastin can cause shifting distribution of fat, and change the relationship between the various facial structures, causing the skin to sag with wrinkles and skin folds.



How does Radiesse Work?
Upon injection, the highly viscoelastic CaHA gel matrix acts as a scaffold and provides immediate volume augmentation. Within the next 9 to 12 months, a firm network of new tissue formation takes place through neocollagenesis, elastin production, angiogenesis, and dermal cell proliferation.
The result is a long-lasting aesthetic improvement for 18 to 24 months or longer with tight and elastic skin and increased skin thickness.

What’s the Difference Between Radiesse And Other Dermal Fillers?
Radiesse is a calcium based (CaHA) dermal filler instead of hyaluronic acid based (HA) fillers, such as the commonly used Juverderm and Rystylane Family. CaHA microspheres presented in Radiesse have the same chemical composition as the inorganic constituent of bone. It is native to the body with an extensive safety profile. The microsphere properties of Radiesse mimic the environment into which it is placed. No migration from the site of injection has been observed. This is a major benefit compared with HA fillers sometimes associated with migration.

What is HyperDilute Radiesse and What Does it Do?
- Acne scars
- Neck, décolletage skin rejuvenation
- Skin laxity and cellulite dimples to buttocks, thighs
- Flaccidity (loose hanging skin with fine wrinkle) of abdomen, arms, knees, and elbows
HyperDilute Radiesse is done with Calcium hydroxyapatite (CaHA) a well-established collagen stimulator. Traditionally CaHA filler is used undiluted with its 1.5 mL product per syringe injected to the skin for volume replacement. In recent years, it has been increasingly used in hyperdiluted form (ie, 1.5 mL of the product plus ≥1.5 mL of diluent), this makes Radiesse a more bio-stimulatory agent rather than a volumizing filler to target the improvement of skin quality and firmness in face, neck and body areas.
Tissues treated with hyper-diluted Radiesse show higher levels of collagen type I, collagen type III, and elastin, promoting greater skin strength, and elasticity, and increasing blood flow and nutrition flow. All these lead to better skin quality in the long term.
FAQ’s
Which Areas Can Radiesse Treat?
- Cheek Augmentation
- Lower face (Chin and Jawline) definition
- Facial wrinkles and folds correction, such as nasolabial folds
- Correction of volume loss in the hands